Polygenic Score (PGS) ID: PGS003748

Predicted Trait
Reported Trait Cigarettes smoked per day
Mapped Trait(s) cigarettes per day measurement (EFO_0006525)
Released in PGS Catalog: June 22, 2023
Download Score FTP directory
Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name GRS46_CPD
Development Method
Name Genome-wide significant SNPs
Parameters NR
Variants
Original Genome Build NR
Number of Variants 46
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000471
Citation (link to publication) Tran JH et al. Transl Vis Sci Technol (2023)
Ancestry Distribution
Source of Variant
Associations (GWAS)
European: 100%
377,334 individuals (100%)
PGS Evaluation
Not Reported: 100%
1 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
GWAS Catalog: GCST007459
Europe PMC: 30643251
 377,334 individuals European NR

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM018505 PSS010997|
Ancestry Not Reported|
14,921 individuals
 PGP000471 |
Tran JH et al. Transl Vis Sci Technol (2023)
 Reported Trait: Cigarettes per day OR: 0.68 [0.43, 0.93] — — — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS010997 — — 14,921 individuals,
40.9 % Male samples
 Mean = 66.1 years Not reported — RS —