| Publication Information (EuropePMC) | |
| Title | Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries |
| PubMed ID | 40778152(Europe PMC) |
| doi | 10.1101/2025.07.21.25331778 |
| Publication Date | July 23, 2025 |
| Journal | medRxiv Preprint |
| Author(s) | Huerta-Chagoya A, Kim J, Mandla R, Lu Y, Suzuki K, Petty LE, Ng HK, Choi J, Lee S, Rout M, Lin K, Adair LS, Adeyemo A, Ahsan H, Akiyama M, An P, Anand SS, Becker DM, Bertoni AG, Bian Z, Bielak LF, Blangero J, Boehnke M, Bottinger EP, Bowden DW, Bragg F, Brody JA, Buchanan TA, Cade BE, Chai J, Chambers JC, Chandak GR, Chang L, Chang K, Chee M, Chen C, Chen Y, Chen Z, Chen YI, Chen J, Chen G, Chen S, Chen W, Cheng C, Cho YS, Choi HS, Chuang L, Cruz M, Cushman M, Das SK, DeFronzo RA, deSilva HJ, Dimitrov L, Doumatey AP, Du S, Duan Q, Duggirala R, Emery LS, Engert JC, Evans DS, Evans MK, Finer S, Florez JC, Floyd JS, Fornage M, Frankel EG, Freedman BI, García-García L, Genter P, Gerstein HC, Goodarzi MO, Gordon-Larsen P, Graff M, Gross M, Guo Y, Guo X, Hai Y, Hanis CL, Hayes M, Horikoshi M, Howard A, Hsu S, Hsueh W, Huang W, Huang M, Hung Y, Hwang MY, Hwu C, Ichihara S, Igase M, Ipp E, Islam MT, Isono M, Jang H, Jasmine F, Jonas JB, Joo YY, Kabagambe E, Kadowaki T, Kamatani Y, Kandeel FR, Kardia SL, Karlson EW, Kasturiratne A, Kato N, Katsuya T, Kaur V, Kawaguchi T, Keaton JM, Kho AN, Khor C, Kibriya M, Kim B, Koh W, Kohara K, Kooner JS, Kooperberg C, Kreienkamp RJ, Lamri A, Lange LA, Lee NR, Lee M, Lee J, Lehman DM, Li L, Li Y, Lim VJ, Liu J, Liu Y, Liu S, Long J, Louie T, Luo X, Lv J, Lynch JA, Maeda S, Mahajan A, Maruthur NM, Matsuda F, McCarthy MI, McKean-Cowdin R, Meigs JB, Millwood IY, Mohlke KL, Motala AA, Nadkarni GN, Nadler JL, Nakatochi M, Nalls MA, Nayak U, Nicolas A, North KE, Nousome D, Okada Y, Pan I, Pankow JS, Paré G, Park J, Park KS, Parra EJ, Patel SR, Pereira MA, Peyser PA, Pirie FJ, Preuss M, Province MA, Psaty BM, Raffel LJ, Raffield LM, Rasmussen-Torvik LJ, Redline S, Reiner AP, Rich SS, Rohde R, Roll K, Roshani R, Rotimi CN, Sabanayagam C, Saleheen D, Sandow K, Schurmann C, Shahriar M, Shaw DM, Sheu WH, Shi J, Shu X, Shuey MM, Siddiqui MK, Smith JA, Sofer T, Spracklen CN, Stilp AM, Sun M, Tabara Y, Tai E, Tajuddin SM, Takahashi A, Takeuchi F, Tan J, Taylor KD, Taylor K, Thameem F, Tong L, Tsai F, Tsao PS, Udler MS, Valladares-Salgado A, van Heel DA, vanDam RM, Varma R, Vora M, Wacher-Rodarte N, Wang Y, Wheeler E, Whitsel EA, Wickremasinghe AR, Wojcik GL, Wong TY, Wu J, Xiang Y, Xiang AH, Yajnik CS, Yamamoto K, Yamauchi T, Yanek LR, Yao J, Yokota M, Yu C, Yuan J, Yusuf S, Zeggini E, Zhang L, Zhang W, Zheng W, Zonderman AB, ENSA Genomics Consortium, Genes & Health Research Team, VA Million Veteran Program, Aguilar-Salinas CA, González-Villalpando C, Haiman CA, Kim YJ, He S. |
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS005361 (DPRISM_T2DPRS_trainedforAMR_EURweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,262,174 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005361/ScoringFiles/PGS005361.txt.gz | |
| PGS005355 (DPRISM_T2DPRS_trainedforAFR_EASweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 981,210 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005355/ScoringFiles/PGS005355.txt.gz | |
| PGS005358 (DPRISM_T2DPRS_trainedforAMR_AFRweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,322,950 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005358/ScoringFiles/PGS005358.txt.gz | |
| PGS005362 (DPRISM_T2DPRS_trainedforAMR_SASweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,191,714 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005362/ScoringFiles/PGS005362.txt.gz | |
| PGS005364 (DPRISM_T2DPRS_trainedforEAS_AMRweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 980,079 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005364/ScoringFiles/PGS005364.txt.gz | |
| PGS005360 (DPRISM_T2DPRS_trainedforAMR_EASweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 941,393 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005360/ScoringFiles/PGS005360.txt.gz | |
| PGS005370 (DPRISM_T2DPRS_trainedforEUR_EASweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 942,728 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005370/ScoringFiles/PGS005370.txt.gz | |
| PGS005375 (DPRISM_T2DPRS_trainedforSAS_EASweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 983,905 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005375/ScoringFiles/PGS005375.txt.gz | |
| PGS005354 (DPRISM_T2DPRS_trainedforAFR_AMRweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,642,045 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005354/ScoringFiles/PGS005354.txt.gz | |
| PGS005356 (DPRISM_T2DPRS_trainedforAFR_EURweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,333,977 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005356/ScoringFiles/PGS005356.txt.gz | |
| PGS005359 (DPRISM_T2DPRS_trainedforAMR_AMRweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,427,746 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005359/ScoringFiles/PGS005359.txt.gz | |
| PGS005372 (DPRISM_T2DPRS_trainedforEUR_SASweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,257,165 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005372/ScoringFiles/PGS005372.txt.gz | |
| PGS005353 (DPRISM_T2DPRS_trainedforAFR_AFRweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 2,325,981 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005353/ScoringFiles/PGS005353.txt.gz | |
| PGS005357 (DPRISM_T2DPRS_trainedforAFR_SASweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,257,227 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005357/ScoringFiles/PGS005357.txt.gz | |
| PGS005365 (DPRISM_T2DPRS_trainedforEAS_EASweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,009,254 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005365/ScoringFiles/PGS005365.txt.gz | |
| PGS005368 (DPRISM_T2DPRS_trainedforEUR_AFRweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,298,374 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005368/ScoringFiles/PGS005368.txt.gz | |
| PGS005371 (DPRISM_T2DPRS_trainedforEUR_EURweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,444,665 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005371/ScoringFiles/PGS005371.txt.gz | |
| PGS005373 (DPRISM_T2DPRS_trainedforSAS_AFRweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,344,157 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005373/ScoringFiles/PGS005373.txt.gz | |
| PGS005377 (DPRISM_T2DPRS_trainedforSAS_SASweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,327,177 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005377/ScoringFiles/PGS005377.txt.gz | |
| PGS005363 (DPRISM_T2DPRS_trainedforEAS_AFRweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 946,015 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005363/ScoringFiles/PGS005363.txt.gz | |
| PGS005366 (DPRISM_T2DPRS_trainedforEAS_EURweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 929,716 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005366/ScoringFiles/PGS005366.txt.gz | |
| PGS005367 (DPRISM_T2DPRS_trainedforEAS_SASweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 976,035 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005367/ScoringFiles/PGS005367.txt.gz | |
| PGS005369 (DPRISM_T2DPRS_trainedforEUR_AMRweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,388,666 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005369/ScoringFiles/PGS005369.txt.gz | |
| PGS005374 (DPRISM_T2DPRS_trainedforSAS_AMRweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,419,570 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005374/ScoringFiles/PGS005374.txt.gz | |
| PGS005376 (DPRISM_T2DPRS_trainedforSAS_EURweights) |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,386,504 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005376/ScoringFiles/PGS005376.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM023199 | PGS005353 (DPRISM_T2DPRS_trainedforAFR_AFRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 1.36 [1.21, 1.53] OR: 1.68 [1.61, 1.76] β: 0.52067 |
AUROC: 0.68035 | R²: 0.12691 | sex, age, genetic principal components | — |
| PPM023200 | PGS005354 (DPRISM_T2DPRS_trainedforAFR_AMRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 1.36 [1.21, 1.53] OR: 1.68 [1.61, 1.76] β: 0.52067 |
AUROC: 0.68035 | R²: 0.12691 | sex, age, genetic principal components | — |
| PPM023201 | PGS005355 (DPRISM_T2DPRS_trainedforAFR_EASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 1.36 [1.21, 1.53] OR: 1.68 [1.61, 1.76] β: 0.52067 |
AUROC: 0.68035 | R²: 0.12691 | sex, age, genetic principal components | — |
| PPM023202 | PGS005356 (DPRISM_T2DPRS_trainedforAFR_EURweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 1.36 [1.21, 1.53] OR: 1.68 [1.61, 1.76] β: 0.52067 |
AUROC: 0.68035 | R²: 0.12691 | sex, age, genetic principal components | — |
| PPM023203 | PGS005357 (DPRISM_T2DPRS_trainedforAFR_SASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 1.36 [1.21, 1.53] OR: 1.68 [1.61, 1.76] β: 0.52067 |
AUROC: 0.68035 | R²: 0.12691 | sex, age, genetic principal components | — |
| PPM023204 | PGS005353 (DPRISM_T2DPRS_trainedforAFR_AFRweights) |
PSS012153| African Ancestry| 2,282 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.71 [1.52, 1.94] β: 0.53912 |
AUROC: 0.64033 | R²: 0.07418 | sex, age, genetic principal components | — |
| PPM023205 | PGS005354 (DPRISM_T2DPRS_trainedforAFR_AMRweights) |
PSS012153| African Ancestry| 2,282 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.71 [1.52, 1.94] β: 0.53912 |
AUROC: 0.64033 | R²: 0.07418 | sex, age, genetic principal components | — |
| PPM023206 | PGS005355 (DPRISM_T2DPRS_trainedforAFR_EASweights) |
PSS012153| African Ancestry| 2,282 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.71 [1.52, 1.94] β: 0.53912 |
AUROC: 0.64033 | R²: 0.07418 | sex, age, genetic principal components | — |
| PPM023207 | PGS005356 (DPRISM_T2DPRS_trainedforAFR_EURweights) |
PSS012153| African Ancestry| 2,282 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.71 [1.52, 1.94] β: 0.53912 |
AUROC: 0.64033 | R²: 0.07418 | sex, age, genetic principal components | — |
| PPM023208 | PGS005357 (DPRISM_T2DPRS_trainedforAFR_SASweights) |
PSS012153| African Ancestry| 2,282 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | β: 0.53912 OR: 1.71 [1.52, 1.94] |
AUROC: 0.64033 | R²: 0.07418 | sex, age, genetic principal components | — |
| PPM023209 | PGS005353 (DPRISM_T2DPRS_trainedforAFR_AFRweights) |
PSS012162| African Ancestry| 1,155 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.46 [1.28, 1.66] β: 0.37919 |
AUROC: 0.62924 | R²: 0.06363 | sex, age, genetic principal components | — |
| PPM023210 | PGS005354 (DPRISM_T2DPRS_trainedforAFR_AMRweights) |
PSS012162| African Ancestry| 1,155 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.46 [1.28, 1.66] β: 0.37919 |
AUROC: 0.62924 | R²: 0.06363 | sex, age, genetic principal components | — |
| PPM023211 | PGS005355 (DPRISM_T2DPRS_trainedforAFR_EASweights) |
PSS012162| African Ancestry| 1,155 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.46 [1.28, 1.66] β: 0.37919 |
AUROC: 0.62924 | R²: 0.06363 | sex, age, genetic principal components | — |
| PPM023212 | PGS005356 (DPRISM_T2DPRS_trainedforAFR_EURweights) |
PSS012162| African Ancestry| 1,155 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.46 [1.28, 1.66] β: 0.37919 |
AUROC: 0.62924 | R²: 0.06363 | sex, age, genetic principal components | — |
| PPM023213 | PGS005357 (DPRISM_T2DPRS_trainedforAFR_SASweights) |
PSS012162| African Ancestry| 1,155 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.46 [1.28, 1.66] β: 0.37919 |
AUROC: 0.62924 | R²: 0.06363 | sex, age, genetic principal components | — |
| PPM023215 | PGS005354 (DPRISM_T2DPRS_trainedforAFR_AMRweights) |
PSS012168| African Ancestry| 2,906 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.62 [2.3, 2.97] β: 0.96137 |
AUROC: 0.74575 | R²: 0.23196 | sex, age, genetic principal components | — |
| PPM023216 | PGS005355 (DPRISM_T2DPRS_trainedforAFR_EASweights) |
PSS012168| African Ancestry| 2,906 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.62 [2.3, 2.97] β: 0.96137 |
AUROC: 0.74575 | R²: 0.23196 | sex, age, genetic principal components | — |
| PPM023217 | PGS005356 (DPRISM_T2DPRS_trainedforAFR_EURweights) |
PSS012168| African Ancestry| 2,906 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.62 [2.3, 2.97] β: 0.96137 |
AUROC: 0.74575 | R²: 0.23196 | sex, age, genetic principal components | — |
| PPM023218 | PGS005357 (DPRISM_T2DPRS_trainedforAFR_SASweights) |
PSS012168| African Ancestry| 2,906 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.62 [2.3, 2.97] β: 0.96137 |
AUROC: 0.74575 | R²: 0.23196 | sex, age, genetic principal components | — |
| PPM023219 | PGS005353 (DPRISM_T2DPRS_trainedforAFR_AFRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 1.39 [1.17, 1.65] β: 0.32872 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023220 | PGS005354 (DPRISM_T2DPRS_trainedforAFR_AMRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 1.39 [1.17, 1.65] β: 0.32872 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023221 | PGS005355 (DPRISM_T2DPRS_trainedforAFR_EASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 1.39 [1.17, 1.65] β: 0.32872 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023222 | PGS005356 (DPRISM_T2DPRS_trainedforAFR_EURweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 1.39 [1.17, 1.65] β: 0.32872 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023223 | PGS005357 (DPRISM_T2DPRS_trainedforAFR_SASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 1.39 [1.17, 1.65] β: 0.32872 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023224 | PGS005353 (DPRISM_T2DPRS_trainedforAFR_AFRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.01 [0.93, 1.11] β: 0.01484 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023225 | PGS005354 (DPRISM_T2DPRS_trainedforAFR_AMRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.01 [0.93, 1.11] β: 0.01484 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023226 | PGS005355 (DPRISM_T2DPRS_trainedforAFR_EASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.01 [0.93, 1.11] β: 0.01484 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023227 | PGS005356 (DPRISM_T2DPRS_trainedforAFR_EURweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.01 [0.93, 1.11] β: 0.01484 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023228 | PGS005357 (DPRISM_T2DPRS_trainedforAFR_SASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.01 [0.93, 1.11] β: 0.01484 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023229 | PGS005353 (DPRISM_T2DPRS_trainedforAFR_AFRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.44 [1.2, 1.74] β: 0.36742 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023230 | PGS005354 (DPRISM_T2DPRS_trainedforAFR_AMRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.44 [1.2, 1.74] β: 0.36742 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023231 | PGS005355 (DPRISM_T2DPRS_trainedforAFR_EASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.44 [1.2, 1.74] β: 0.36742 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023232 | PGS005356 (DPRISM_T2DPRS_trainedforAFR_EURweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.44 [1.2, 1.74] β: 0.36742 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023233 | PGS005357 (DPRISM_T2DPRS_trainedforAFR_SASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.44 [1.2, 1.74] β: 0.36742 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023234 | PGS005353 (DPRISM_T2DPRS_trainedforAFR_AFRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.28 [1.18, 1.39] β: 0.24486 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023235 | PGS005354 (DPRISM_T2DPRS_trainedforAFR_AMRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.28 [1.18, 1.39] β: 0.24486 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023236 | PGS005355 (DPRISM_T2DPRS_trainedforAFR_EASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.28 [1.18, 1.39] β: 0.24486 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023238 | PGS005357 (DPRISM_T2DPRS_trainedforAFR_SASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.28 [1.18, 1.39] β: 0.24486 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023239 | PGS005353 (DPRISM_T2DPRS_trainedforAFR_AFRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.26 [1.13, 1.4] β: 0.22875 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023240 | PGS005354 (DPRISM_T2DPRS_trainedforAFR_AMRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.26 [1.13, 1.4] β: 0.22875 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023241 | PGS005355 (DPRISM_T2DPRS_trainedforAFR_EASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.26 [1.13, 1.4] β: 0.22875 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023242 | PGS005356 (DPRISM_T2DPRS_trainedforAFR_EURweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.26 [1.13, 1.4] β: 0.22875 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023243 | PGS005357 (DPRISM_T2DPRS_trainedforAFR_SASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.26 [1.13, 1.4] β: 0.22875 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023244 | PGS005353 (DPRISM_T2DPRS_trainedforAFR_AFRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 0.99 [0.93, 1.05] β: -0.01123 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023245 | PGS005354 (DPRISM_T2DPRS_trainedforAFR_AMRweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 0.99 [0.93, 1.05] β: -0.01123 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023246 | PGS005355 (DPRISM_T2DPRS_trainedforAFR_EASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 0.99 [0.93, 1.05] β: -0.01123 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023247 | PGS005356 (DPRISM_T2DPRS_trainedforAFR_EURweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 0.99 [0.93, 1.05] β: -0.01123 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023248 | PGS005357 (DPRISM_T2DPRS_trainedforAFR_SASweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 0.99 [0.93, 1.05] β: -0.01123 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023249 | PGS005358 (DPRISM_T2DPRS_trainedforAMR_AFRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 2.13 [1.8, 2.52] OR: 2.86 [2.68, 3.06] β: 1.05143 |
AUROC: 0.76555 | R²: 0.27402 | sex, age, genetic principal components | — |
| PPM023250 | PGS005359 (DPRISM_T2DPRS_trainedforAMR_AMRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 2.13 [1.8, 2.52] OR: 2.86 [2.68, 3.06] β: 1.05143 |
AUROC: 0.76555 | R²: 0.27402 | sex, age, genetic principal components | — |
| PPM023251 | PGS005360 (DPRISM_T2DPRS_trainedforAMR_EASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 2.13 [1.8, 2.52] OR: 2.86 [2.68, 3.06] β: 1.05143 |
AUROC: 0.76555 | R²: 0.27402 | sex, age, genetic principal components | — |
| PPM023252 | PGS005361 (DPRISM_T2DPRS_trainedforAMR_EURweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 2.13 [1.8, 2.52] OR: 2.86 [2.68, 3.06] β: 1.05143 |
AUROC: 0.76555 | R²: 0.27402 | sex, age, genetic principal components | — |
| PPM023253 | PGS005362 (DPRISM_T2DPRS_trainedforAMR_SASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 2.13 [1.8, 2.52] OR: 2.86 [2.68, 3.06] β: 1.05143 |
AUROC: 0.76555 | R²: 0.27402 | sex, age, genetic principal components | — |
| PPM023254 | PGS005358 (DPRISM_T2DPRS_trainedforAMR_AFRweights) |
PSS012156| Hispanic or Latin American Ancestry| 4,126 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 3.48 [3.02, 4.01] β: 1.24666 |
AUROC: 0.72336 | R²: 0.17962 | sex, age, genetic principal components | — |
| PPM023256 | PGS005360 (DPRISM_T2DPRS_trainedforAMR_EASweights) |
PSS012156| Hispanic or Latin American Ancestry| 4,126 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 3.48 [3.02, 4.01] β: 1.24666 |
AUROC: 0.72336 | R²: 0.17962 | sex, age, genetic principal components | — |
| PPM023257 | PGS005361 (DPRISM_T2DPRS_trainedforAMR_EURweights) |
PSS012156| Hispanic or Latin American Ancestry| 4,126 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 3.48 [3.02, 4.01] β: 1.24666 |
AUROC: 0.72336 | R²: 0.17962 | sex, age, genetic principal components | — |
| PPM023258 | PGS005362 (DPRISM_T2DPRS_trainedforAMR_SASweights) |
PSS012156| Hispanic or Latin American Ancestry| 4,126 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 3.48 [3.02, 4.01] β: 1.24666 |
AUROC: 0.72336 | R²: 0.17962 | sex, age, genetic principal components | — |
| PPM023259 | PGS005358 (DPRISM_T2DPRS_trainedforAMR_AFRweights) |
PSS012164| Hispanic or Latin American Ancestry| 1,086 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.6 [2.15, 3.14] β: 0.95481 |
AUROC: 0.72125 | R²: 0.17352 | sex, age, genetic principal components | — |
| PPM023260 | PGS005359 (DPRISM_T2DPRS_trainedforAMR_AMRweights) |
PSS012164| Hispanic or Latin American Ancestry| 1,086 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.6 [2.15, 3.14] β: 0.95481 |
AUROC: 0.72125 | R²: 0.17352 | sex, age, genetic principal components | — |
| PPM023261 | PGS005360 (DPRISM_T2DPRS_trainedforAMR_EASweights) |
PSS012164| Hispanic or Latin American Ancestry| 1,086 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.6 [2.15, 3.14] β: 0.95481 |
AUROC: 0.72125 | R²: 0.17352 | sex, age, genetic principal components | — |
| PPM023262 | PGS005361 (DPRISM_T2DPRS_trainedforAMR_EURweights) |
PSS012164| Hispanic or Latin American Ancestry| 1,086 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.6 [2.15, 3.14] β: 0.95481 |
AUROC: 0.72125 | R²: 0.17352 | sex, age, genetic principal components | — |
| PPM023263 | PGS005362 (DPRISM_T2DPRS_trainedforAMR_SASweights) |
PSS012164| Hispanic or Latin American Ancestry| 1,086 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.6 [2.15, 3.14] β: 0.95481 |
AUROC: 0.72125 | R²: 0.17352 | sex, age, genetic principal components | — |
| PPM023264 | PGS005358 (DPRISM_T2DPRS_trainedforAMR_AFRweights) |
PSS012165| Hispanic or Latin American Ancestry| 1,683 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.15 [1.85, 2.5] β: 0.76689 |
AUROC: 0.71248 | R²: 0.16347 | sex, age, genetic principal components | — |
| PPM023265 | PGS005359 (DPRISM_T2DPRS_trainedforAMR_AMRweights) |
PSS012165| Hispanic or Latin American Ancestry| 1,683 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.15 [1.85, 2.5] β: 0.76689 |
AUROC: 0.71248 | R²: 0.16347 | sex, age, genetic principal components | — |
| PPM023266 | PGS005360 (DPRISM_T2DPRS_trainedforAMR_EASweights) |
PSS012165| Hispanic or Latin American Ancestry| 1,683 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.15 [1.85, 2.5] β: 0.76689 |
AUROC: 0.71248 | R²: 0.16347 | sex, age, genetic principal components | — |
| PPM023267 | PGS005361 (DPRISM_T2DPRS_trainedforAMR_EURweights) |
PSS012165| Hispanic or Latin American Ancestry| 1,683 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.15 [1.85, 2.5] β: 0.76689 |
AUROC: 0.71248 | R²: 0.16347 | sex, age, genetic principal components | — |
| PPM023268 | PGS005362 (DPRISM_T2DPRS_trainedforAMR_SASweights) |
PSS012165| Hispanic or Latin American Ancestry| 1,683 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.15 [1.85, 2.5] β: 0.76689 |
AUROC: 0.71248 | R²: 0.16347 | sex, age, genetic principal components | — |
| PPM023270 | PGS005359 (DPRISM_T2DPRS_trainedforAMR_AMRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 2.08 [1.73, 2.51] β: 0.73382 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023271 | PGS005360 (DPRISM_T2DPRS_trainedforAMR_EASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 2.08 [1.73, 2.51] β: 0.73382 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023272 | PGS005361 (DPRISM_T2DPRS_trainedforAMR_EURweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 2.08 [1.73, 2.51] β: 0.73382 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023273 | PGS005362 (DPRISM_T2DPRS_trainedforAMR_SASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 2.08 [1.73, 2.51] β: 0.73382 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023274 | PGS005358 (DPRISM_T2DPRS_trainedforAMR_AFRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.05 [0.93, 1.18] β: 0.04638 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023275 | PGS005359 (DPRISM_T2DPRS_trainedforAMR_AMRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.05 [0.93, 1.18] β: 0.04638 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023276 | PGS005360 (DPRISM_T2DPRS_trainedforAMR_EASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.05 [0.93, 1.18] β: 0.04638 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023277 | PGS005361 (DPRISM_T2DPRS_trainedforAMR_EURweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.05 [0.93, 1.18] β: 0.04638 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023278 | PGS005362 (DPRISM_T2DPRS_trainedforAMR_SASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.05 [0.93, 1.18] β: 0.04638 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023279 | PGS005358 (DPRISM_T2DPRS_trainedforAMR_AFRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.87 [1.56, 2.22] β: 0.6235 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023280 | PGS005359 (DPRISM_T2DPRS_trainedforAMR_AMRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.87 [1.56, 2.22] β: 0.6235 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023281 | PGS005360 (DPRISM_T2DPRS_trainedforAMR_EASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.87 [1.56, 2.22] β: 0.6235 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023282 | PGS005361 (DPRISM_T2DPRS_trainedforAMR_EURweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.87 [1.56, 2.22] β: 0.6235 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023283 | PGS005362 (DPRISM_T2DPRS_trainedforAMR_SASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.87 [1.56, 2.22] β: 0.6235 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023284 | PGS005358 (DPRISM_T2DPRS_trainedforAMR_AFRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.57 [1.43, 1.73] β: 0.45344 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023285 | PGS005359 (DPRISM_T2DPRS_trainedforAMR_AMRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.57 [1.43, 1.73] β: 0.45344 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023286 | PGS005360 (DPRISM_T2DPRS_trainedforAMR_EASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.57 [1.43, 1.73] β: 0.45344 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023287 | PGS005361 (DPRISM_T2DPRS_trainedforAMR_EURweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.57 [1.43, 1.73] β: 0.45344 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023288 | PGS005362 (DPRISM_T2DPRS_trainedforAMR_SASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.57 [1.43, 1.73] β: 0.45344 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023289 | PGS005358 (DPRISM_T2DPRS_trainedforAMR_AFRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.58 [1.41, 1.78] β: 0.45816 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023290 | PGS005359 (DPRISM_T2DPRS_trainedforAMR_AMRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.58 [1.41, 1.78] β: 0.45816 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023291 | PGS005360 (DPRISM_T2DPRS_trainedforAMR_EASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.58 [1.41, 1.78] β: 0.45816 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023292 | PGS005361 (DPRISM_T2DPRS_trainedforAMR_EURweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.58 [1.41, 1.78] β: 0.45816 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023293 | PGS005362 (DPRISM_T2DPRS_trainedforAMR_SASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.58 [1.41, 1.78] β: 0.45816 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023294 | PGS005358 (DPRISM_T2DPRS_trainedforAMR_AFRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 1.16 [1.08, 1.25] β: 0.14943 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023295 | PGS005359 (DPRISM_T2DPRS_trainedforAMR_AMRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 1.16 [1.08, 1.25] β: 0.14943 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023296 | PGS005360 (DPRISM_T2DPRS_trainedforAMR_EASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 1.16 [1.08, 1.25] β: 0.14943 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023297 | PGS005361 (DPRISM_T2DPRS_trainedforAMR_EURweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 1.16 [1.08, 1.25] β: 0.14943 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023298 | PGS005362 (DPRISM_T2DPRS_trainedforAMR_SASweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 1.16 [1.08, 1.25] β: 0.14943 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023299 | PGS005363 (DPRISM_T2DPRS_trainedforEAS_AFRweights) |
PSS012149| East Asian Ancestry| 917 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.56 [2.11, 3.12] β: 0.94195 |
AUROC: 0.80354 | R²: 0.32266 | sex, age, genetic principal components | — |
| PPM023300 | PGS005364 (DPRISM_T2DPRS_trainedforEAS_AMRweights) |
PSS012149| East Asian Ancestry| 917 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.56 [2.11, 3.12] β: 0.94195 |
AUROC: 0.80354 | R²: 0.32266 | sex, age, genetic principal components | — |
| PPM023301 | PGS005365 (DPRISM_T2DPRS_trainedforEAS_EASweights) |
PSS012149| East Asian Ancestry| 917 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.56 [2.11, 3.12] β: 0.94195 |
AUROC: 0.80354 | R²: 0.32266 | sex, age, genetic principal components | — |
| PPM023302 | PGS005366 (DPRISM_T2DPRS_trainedforEAS_EURweights) |
PSS012149| East Asian Ancestry| 917 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.56 [2.11, 3.12] β: 0.94195 |
AUROC: 0.80354 | R²: 0.32266 | sex, age, genetic principal components | — |
| PPM023303 | PGS005367 (DPRISM_T2DPRS_trainedforEAS_SASweights) |
PSS012149| East Asian Ancestry| 917 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.56 [2.11, 3.12] β: 0.94195 |
AUROC: 0.80354 | R²: 0.32266 | sex, age, genetic principal components | — |
| PPM023304 | PGS005363 (DPRISM_T2DPRS_trainedforEAS_AFRweights) |
PSS012152| East Asian Ancestry| 2,846 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.25 [2.05, 2.48] β: 0.81178 |
AUROC: 0.72251 | R²: 0.18468 | sex, age, genetic principal components | — |
| PPM023305 | PGS005364 (DPRISM_T2DPRS_trainedforEAS_AMRweights) |
PSS012152| East Asian Ancestry| 2,846 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.25 [2.05, 2.48] β: 0.81178 |
AUROC: 0.72251 | R²: 0.18468 | sex, age, genetic principal components | — |
| PPM023306 | PGS005365 (DPRISM_T2DPRS_trainedforEAS_EASweights) |
PSS012152| East Asian Ancestry| 2,846 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.25 [2.05, 2.48] β: 0.81178 |
AUROC: 0.72251 | R²: 0.18468 | sex, age, genetic principal components | — |
| PPM023307 | PGS005366 (DPRISM_T2DPRS_trainedforEAS_EURweights) |
PSS012152| East Asian Ancestry| 2,846 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.25 [2.05, 2.48] β: 0.81178 |
AUROC: 0.72251 | R²: 0.18468 | sex, age, genetic principal components | — |
| PPM023308 | PGS005367 (DPRISM_T2DPRS_trainedforEAS_SASweights) |
PSS012152| East Asian Ancestry| 2,846 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.25 [2.05, 2.48] β: 0.81178 |
AUROC: 0.72251 | R²: 0.18468 | sex, age, genetic principal components | — |
| PPM023309 | PGS005363 (DPRISM_T2DPRS_trainedforEAS_AFRweights) |
PSS012154| East Asian Ancestry| 804 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.96 [1.6, 2.39] β: 0.67233 |
AUROC: 0.74954 | R²: 0.20701 | sex, age, genetic principal components | — |
| PPM023310 | PGS005364 (DPRISM_T2DPRS_trainedforEAS_AMRweights) |
PSS012154| East Asian Ancestry| 804 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.96 [1.6, 2.39] β: 0.67233 |
AUROC: 0.74954 | R²: 0.20701 | sex, age, genetic principal components | — |
| PPM023311 | PGS005365 (DPRISM_T2DPRS_trainedforEAS_EASweights) |
PSS012154| East Asian Ancestry| 804 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.96 [1.6, 2.39] β: 0.67233 |
AUROC: 0.74954 | R²: 0.20701 | sex, age, genetic principal components | — |
| PPM023313 | PGS005367 (DPRISM_T2DPRS_trainedforEAS_SASweights) |
PSS012154| East Asian Ancestry| 804 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.96 [1.6, 2.39] β: 0.67233 |
AUROC: 0.74954 | R²: 0.20701 | sex, age, genetic principal components | — |
| PPM023314 | PGS005363 (DPRISM_T2DPRS_trainedforEAS_AFRweights) |
PSS012159| East Asian Ancestry| 9,144 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.78 [1.66, 1.9] β: 0.57569 |
AUROC: 0.71515 | R²: 0.14166 | sex, age, genetic principal components | — |
| PPM023315 | PGS005364 (DPRISM_T2DPRS_trainedforEAS_AMRweights) |
PSS012159| East Asian Ancestry| 9,144 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.78 [1.66, 1.9] β: 0.57569 |
AUROC: 0.71515 | R²: 0.14166 | sex, age, genetic principal components | — |
| PPM023316 | PGS005365 (DPRISM_T2DPRS_trainedforEAS_EASweights) |
PSS012159| East Asian Ancestry| 9,144 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | β: 0.57569 OR: 1.78 [1.66, 1.9] |
AUROC: 0.71515 | R²: 0.14166 | sex, age, genetic principal components | — |
| PPM023317 | PGS005366 (DPRISM_T2DPRS_trainedforEAS_EURweights) |
PSS012159| East Asian Ancestry| 9,144 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.78 [1.66, 1.9] β: 0.57569 |
AUROC: 0.71515 | R²: 0.14166 | sex, age, genetic principal components | — |
| PPM023318 | PGS005367 (DPRISM_T2DPRS_trainedforEAS_SASweights) |
PSS012159| East Asian Ancestry| 9,144 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.78 [1.66, 1.9] β: 0.57569 |
AUROC: 0.71515 | R²: 0.14166 | sex, age, genetic principal components | — |
| PPM023319 | PGS005363 (DPRISM_T2DPRS_trainedforEAS_AFRweights) |
PSS012160| East Asian Ancestry| 13,197 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.86 [2.69, 3.04] β: 1.05048 |
AUROC: 0.79138 | R²: 0.2399 | sex, age, genetic principal components | — |
| PPM023320 | PGS005364 (DPRISM_T2DPRS_trainedforEAS_AMRweights) |
PSS012160| East Asian Ancestry| 13,197 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.86 [2.69, 3.04] β: 1.05048 |
AUROC: 0.79138 | R²: 0.2399 | sex, age, genetic principal components | — |
| PPM023321 | PGS005365 (DPRISM_T2DPRS_trainedforEAS_EASweights) |
PSS012160| East Asian Ancestry| 13,197 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.86 [2.69, 3.04] β: 1.05048 |
AUROC: 0.79138 | R²: 0.2399 | sex, age, genetic principal components | — |
| PPM023322 | PGS005366 (DPRISM_T2DPRS_trainedforEAS_EURweights) |
PSS012160| East Asian Ancestry| 13,197 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.86 [2.69, 3.04] β: 1.05048 |
AUROC: 0.79138 | R²: 0.2399 | sex, age, genetic principal components | — |
| PPM023323 | PGS005367 (DPRISM_T2DPRS_trainedforEAS_SASweights) |
PSS012160| East Asian Ancestry| 13,197 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.86 [2.69, 3.04] β: 1.05048 |
AUROC: 0.79138 | R²: 0.2399 | sex, age, genetic principal components | — |
| PPM023324 | PGS005363 (DPRISM_T2DPRS_trainedforEAS_AFRweights) |
PSS012166| East Asian Ancestry| 1,660 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.45 [2.12, 2.83] β: 0.89724 |
AUROC: 0.86 | R²: 0.47165 | sex, age, genetic principal components | — |
| PPM023325 | PGS005364 (DPRISM_T2DPRS_trainedforEAS_AMRweights) |
PSS012166| East Asian Ancestry| 1,660 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.45 [2.12, 2.83] β: 0.89724 |
AUROC: 0.86 | R²: 0.47165 | sex, age, genetic principal components | — |
| PPM023326 | PGS005365 (DPRISM_T2DPRS_trainedforEAS_EASweights) |
PSS012166| East Asian Ancestry| 1,660 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.45 [2.12, 2.83] β: 0.89724 |
AUROC: 0.86 | R²: 0.47165 | sex, age, genetic principal components | — |
| PPM023327 | PGS005366 (DPRISM_T2DPRS_trainedforEAS_EURweights) |
PSS012166| East Asian Ancestry| 1,660 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.45 [2.12, 2.83] β: 0.89724 |
AUROC: 0.86 | R²: 0.47165 | sex, age, genetic principal components | — |
| PPM023328 | PGS005367 (DPRISM_T2DPRS_trainedforEAS_SASweights) |
PSS012166| East Asian Ancestry| 1,660 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.45 [2.12, 2.83] β: 0.89724 |
AUROC: 0.86 | R²: 0.47165 | sex, age, genetic principal components | — |
| PPM023329 | PGS005363 (DPRISM_T2DPRS_trainedforEAS_AFRweights) |
PSS012167| East Asian Ancestry| 3,634 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 4.35 [3.89, 4.86] β: 1.46928 |
AUROC: 0.83429 | R²: 0.41128 | sex, age, genetic principal components | — |
| PPM023330 | PGS005364 (DPRISM_T2DPRS_trainedforEAS_AMRweights) |
PSS012167| East Asian Ancestry| 3,634 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 4.35 [3.89, 4.86] β: 1.46928 |
AUROC: 0.83429 | R²: 0.41128 | sex, age, genetic principal components | — |
| PPM023332 | PGS005366 (DPRISM_T2DPRS_trainedforEAS_EURweights) |
PSS012167| East Asian Ancestry| 3,634 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 4.35 [3.89, 4.86] β: 1.46928 |
AUROC: 0.83429 | R²: 0.41128 | sex, age, genetic principal components | — |
| PPM023333 | PGS005367 (DPRISM_T2DPRS_trainedforEAS_SASweights) |
PSS012167| East Asian Ancestry| 3,634 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 4.35 [3.89, 4.86] β: 1.46928 |
AUROC: 0.83429 | R²: 0.41128 | sex, age, genetic principal components | — |
| PPM023334 | PGS005368 (DPRISM_T2DPRS_trainedforEUR_AFRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 2.18 [2.05, 2.33] OR: 2.64 [2.56, 2.72] β: 0.96963 |
AUROC: 0.7571 | R²: 0.2129 | sex, age, genetic principal components | — |
| PPM023335 | PGS005369 (DPRISM_T2DPRS_trainedforEUR_AMRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 2.18 [2.05, 2.33] OR: 2.64 [2.56, 2.72] β: 0.96963 |
AUROC: 0.7571 | R²: 0.2129 | sex, age, genetic principal components | — |
| PPM023336 | PGS005370 (DPRISM_T2DPRS_trainedforEUR_EASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 2.18 [2.05, 2.33] OR: 2.64 [2.56, 2.72] β: 0.96963 |
AUROC: 0.7571 | R²: 0.2129 | sex, age, genetic principal components | — |
| PPM023337 | PGS005371 (DPRISM_T2DPRS_trainedforEUR_EURweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 2.18 [2.05, 2.33] OR: 2.64 [2.56, 2.72] β: 0.96963 |
AUROC: 0.7571 | R²: 0.2129 | sex, age, genetic principal components | — |
| PPM023338 | PGS005372 (DPRISM_T2DPRS_trainedforEUR_SASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | HR: 2.18 [2.05, 2.33] OR: 2.64 [2.56, 2.72] β: 0.96963 |
AUROC: 0.7571 | R²: 0.2129 | sex, age, genetic principal components | — |
| PPM023339 | PGS005368 (DPRISM_T2DPRS_trainedforEUR_AFRweights) |
PSS012155| European Ancestry| 7,573 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.96 [1.81, 2.12] β: 0.67282 |
AUROC: 0.69233 | R²: 0.10551 | sex, age, genetic principal components | — |
| PPM023340 | PGS005369 (DPRISM_T2DPRS_trainedforEUR_AMRweights) |
PSS012155| European Ancestry| 7,573 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.96 [1.81, 2.12] β: 0.67282 |
AUROC: 0.69233 | R²: 0.10551 | sex, age, genetic principal components | — |
| PPM023341 | PGS005370 (DPRISM_T2DPRS_trainedforEUR_EASweights) |
PSS012155| European Ancestry| 7,573 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.96 [1.81, 2.12] β: 0.67282 |
AUROC: 0.69233 | R²: 0.10551 | sex, age, genetic principal components | — |
| PPM023342 | PGS005371 (DPRISM_T2DPRS_trainedforEUR_EURweights) |
PSS012155| European Ancestry| 7,573 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.96 [1.81, 2.12] β: 0.67282 |
AUROC: 0.69233 | R²: 0.10551 | sex, age, genetic principal components | — |
| PPM023343 | PGS005372 (DPRISM_T2DPRS_trainedforEUR_SASweights) |
PSS012155| European Ancestry| 7,573 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.96 [1.81, 2.12] β: 0.67282 |
AUROC: 0.69233 | R²: 0.10551 | sex, age, genetic principal components | — |
| PPM023344 | PGS005368 (DPRISM_T2DPRS_trainedforEUR_AFRweights) |
PSS012158| European Ancestry| 21,769 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.16 [2.07, 2.25] β: 0.76796 |
AUROC: 0.72142 | R²: 0.14038 | sex, age, genetic principal components | — |
| PPM023345 | PGS005369 (DPRISM_T2DPRS_trainedforEUR_AMRweights) |
PSS012158| European Ancestry| 21,769 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.16 [2.07, 2.25] β: 0.76796 |
AUROC: 0.72142 | R²: 0.14038 | sex, age, genetic principal components | — |
| PPM023346 | PGS005370 (DPRISM_T2DPRS_trainedforEUR_EASweights) |
PSS012158| European Ancestry| 21,769 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.16 [2.07, 2.25] β: 0.76796 |
AUROC: 0.72142 | R²: 0.14038 | sex, age, genetic principal components | — |
| PPM023347 | PGS005371 (DPRISM_T2DPRS_trainedforEUR_EURweights) |
PSS012158| European Ancestry| 21,769 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.16 [2.07, 2.25] β: 0.76796 |
AUROC: 0.72142 | R²: 0.14038 | sex, age, genetic principal components | — |
| PPM023348 | PGS005372 (DPRISM_T2DPRS_trainedforEUR_SASweights) |
PSS012158| European Ancestry| 21,769 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.16 [2.07, 2.25] β: 0.76796 |
AUROC: 0.72142 | R²: 0.14038 | sex, age, genetic principal components | — |
| PPM023349 | PGS005368 (DPRISM_T2DPRS_trainedforEUR_AFRweights) |
PSS012163| European Ancestry| 23,183 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.23 [2.15, 2.32] β: 0.80251 |
AUROC: 0.72972 | R²: 0.13778 | sex, age, genetic principal components | — |
| PPM023350 | PGS005369 (DPRISM_T2DPRS_trainedforEUR_AMRweights) |
PSS012163| European Ancestry| 23,183 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.23 [2.15, 2.32] β: 0.80251 |
AUROC: 0.72972 | R²: 0.13778 | sex, age, genetic principal components | — |
| PPM023351 | PGS005370 (DPRISM_T2DPRS_trainedforEUR_EASweights) |
PSS012163| European Ancestry| 23,183 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.23 [2.15, 2.32] β: 0.80251 |
AUROC: 0.72972 | R²: 0.13778 | sex, age, genetic principal components | — |
| PPM023352 | PGS005371 (DPRISM_T2DPRS_trainedforEUR_EURweights) |
PSS012163| European Ancestry| 23,183 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.23 [2.15, 2.32] β: 0.80251 |
AUROC: 0.72972 | R²: 0.13778 | sex, age, genetic principal components | — |
| PPM023353 | PGS005372 (DPRISM_T2DPRS_trainedforEUR_SASweights) |
PSS012163| European Ancestry| 23,183 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.23 [2.15, 2.32] β: 0.80251 |
AUROC: 0.72972 | R²: 0.13778 | sex, age, genetic principal components | — |
| PPM023355 | PGS005369 (DPRISM_T2DPRS_trainedforEUR_AMRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 1.67 [1.44, 1.93] β: 0.51204 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023356 | PGS005370 (DPRISM_T2DPRS_trainedforEUR_EASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 1.67 [1.44, 1.93] β: 0.51204 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023357 | PGS005371 (DPRISM_T2DPRS_trainedforEUR_EURweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 1.67 [1.44, 1.93] β: 0.51204 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023358 | PGS005372 (DPRISM_T2DPRS_trainedforEUR_SASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 1.67 [1.44, 1.93] β: 0.51204 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023359 | PGS005368 (DPRISM_T2DPRS_trainedforEUR_AFRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.02 [0.96, 1.07] β: 0.01517 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023360 | PGS005369 (DPRISM_T2DPRS_trainedforEUR_AMRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.02 [0.96, 1.07] β: 0.01517 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023361 | PGS005370 (DPRISM_T2DPRS_trainedforEUR_EASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.02 [0.96, 1.07] β: 0.01517 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023362 | PGS005371 (DPRISM_T2DPRS_trainedforEUR_EURweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.02 [0.96, 1.07] β: 0.01517 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023363 | PGS005372 (DPRISM_T2DPRS_trainedforEUR_SASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Ischemic stroke | OR: 1.02 [0.96, 1.07] β: 0.01517 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023364 | PGS005368 (DPRISM_T2DPRS_trainedforEUR_AFRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.46 [1.28, 1.68] β: 0.37999 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023365 | PGS005369 (DPRISM_T2DPRS_trainedforEUR_AMRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.46 [1.28, 1.68] β: 0.37999 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023366 | PGS005370 (DPRISM_T2DPRS_trainedforEUR_EASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.46 [1.28, 1.68] β: 0.37999 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023367 | PGS005371 (DPRISM_T2DPRS_trainedforEUR_EURweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.46 [1.28, 1.68] β: 0.37999 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023368 | PGS005372 (DPRISM_T2DPRS_trainedforEUR_SASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: End-stage diabetic nephropathy | OR: 1.46 [1.28, 1.68] β: 0.37999 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023369 | PGS005368 (DPRISM_T2DPRS_trainedforEUR_AFRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.42 [1.34, 1.5] β: 0.34732 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023370 | PGS005369 (DPRISM_T2DPRS_trainedforEUR_AMRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.42 [1.34, 1.5] β: 0.34732 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023371 | PGS005370 (DPRISM_T2DPRS_trainedforEUR_EASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.42 [1.34, 1.5] β: 0.34732 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023372 | PGS005371 (DPRISM_T2DPRS_trainedforEUR_EURweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.42 [1.34, 1.5] β: 0.34732 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023373 | PGS005372 (DPRISM_T2DPRS_trainedforEUR_SASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.42 [1.34, 1.5] β: 0.34732 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023374 | PGS005368 (DPRISM_T2DPRS_trainedforEUR_AFRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.25 [1.18, 1.32] β: 0.2209 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023375 | PGS005369 (DPRISM_T2DPRS_trainedforEUR_AMRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.25 [1.18, 1.32] β: 0.2209 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023376 | PGS005370 (DPRISM_T2DPRS_trainedforEUR_EASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.25 [1.18, 1.32] β: 0.2209 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023377 | PGS005371 (DPRISM_T2DPRS_trainedforEUR_EURweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.25 [1.18, 1.32] β: 0.2209 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023378 | PGS005372 (DPRISM_T2DPRS_trainedforEUR_SASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic nephropathy | OR: 1.25 [1.18, 1.32] β: 0.2209 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023379 | PGS005368 (DPRISM_T2DPRS_trainedforEUR_AFRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 1.03 [0.99, 1.06] β: 0.02493 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023380 | PGS005369 (DPRISM_T2DPRS_trainedforEUR_AMRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 1.03 [0.99, 1.06] β: 0.02493 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023381 | PGS005370 (DPRISM_T2DPRS_trainedforEUR_EASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 1.03 [0.99, 1.06] β: 0.02493 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023382 | PGS005371 (DPRISM_T2DPRS_trainedforEUR_EURweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 1.03 [0.99, 1.06] β: 0.02493 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023383 | PGS005372 (DPRISM_T2DPRS_trainedforEUR_SASweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Cardiovascular disease | OR: 1.03 [0.99, 1.06] β: 0.02493 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023384 | PGS005373 (DPRISM_T2DPRS_trainedforSAS_AFRweights) |
PSS012146| South Asian Ancestry| 1,397 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.2 [1.92, 2.51] β: 0.78618 |
AUROC: 0.71851 | R²: 0.18837 | sex, age, genetic principal components | — |
| PPM023385 | PGS005374 (DPRISM_T2DPRS_trainedforSAS_AMRweights) |
PSS012146| South Asian Ancestry| 1,397 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.2 [1.92, 2.51] β: 0.78618 |
AUROC: 0.71851 | R²: 0.18837 | sex, age, genetic principal components | — |
| PPM023386 | PGS005375 (DPRISM_T2DPRS_trainedforSAS_EASweights) |
PSS012146| South Asian Ancestry| 1,397 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.2 [1.92, 2.51] β: 0.78618 |
AUROC: 0.71851 | R²: 0.18837 | sex, age, genetic principal components | — |
| PPM023387 | PGS005376 (DPRISM_T2DPRS_trainedforSAS_EURweights) |
PSS012146| South Asian Ancestry| 1,397 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.2 [1.92, 2.51] β: 0.78618 |
AUROC: 0.71851 | R²: 0.18837 | sex, age, genetic principal components | — |
| PPM023388 | PGS005377 (DPRISM_T2DPRS_trainedforSAS_SASweights) |
PSS012146| South Asian Ancestry| 1,397 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.2 [1.92, 2.51] β: 0.78618 |
AUROC: 0.71851 | R²: 0.18837 | sex, age, genetic principal components | — |
| PPM023389 | PGS005373 (DPRISM_T2DPRS_trainedforSAS_AFRweights) |
PSS012147| South Asian Ancestry| 426 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.26 [1.74, 2.93] β: 0.81334 |
AUROC: 0.80144 | R²: 0.32092 | sex, age, genetic principal components | — |
| PPM023390 | PGS005374 (DPRISM_T2DPRS_trainedforSAS_AMRweights) |
PSS012147| South Asian Ancestry| 426 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.26 [1.74, 2.93] β: 0.81334 |
AUROC: 0.80144 | R²: 0.32092 | sex, age, genetic principal components | — |
| PPM023391 | PGS005375 (DPRISM_T2DPRS_trainedforSAS_EASweights) |
PSS012147| South Asian Ancestry| 426 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.26 [1.74, 2.93] β: 0.81334 |
AUROC: 0.80144 | R²: 0.32092 | sex, age, genetic principal components | — |
| PPM023392 | PGS005376 (DPRISM_T2DPRS_trainedforSAS_EURweights) |
PSS012147| South Asian Ancestry| 426 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.26 [1.74, 2.93] β: 0.81334 |
AUROC: 0.80144 | R²: 0.32092 | sex, age, genetic principal components | — |
| PPM023393 | PGS005377 (DPRISM_T2DPRS_trainedforSAS_SASweights) |
PSS012147| South Asian Ancestry| 426 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.26 [1.74, 2.93] β: 0.81334 |
AUROC: 0.80144 | R²: 0.32092 | sex, age, genetic principal components | — |
| PPM023394 | PGS005373 (DPRISM_T2DPRS_trainedforSAS_AFRweights) |
PSS012157| South Asian Ancestry| 630 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.77 [1.47, 2.13] β: 0.56903 |
AUROC: 0.67322 | R²: 0.11799 | sex, age, genetic principal components | — |
| PPM023395 | PGS005374 (DPRISM_T2DPRS_trainedforSAS_AMRweights) |
PSS012157| South Asian Ancestry| 630 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.77 [1.47, 2.13] β: 0.56903 |
AUROC: 0.67322 | R²: 0.11799 | sex, age, genetic principal components | — |
| PPM023396 | PGS005375 (DPRISM_T2DPRS_trainedforSAS_EASweights) |
PSS012157| South Asian Ancestry| 630 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.77 [1.47, 2.13] β: 0.56903 |
AUROC: 0.67322 | R²: 0.11799 | sex, age, genetic principal components | — |
| PPM023397 | PGS005376 (DPRISM_T2DPRS_trainedforSAS_EURweights) |
PSS012157| South Asian Ancestry| 630 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.77 [1.47, 2.13] β: 0.56903 |
AUROC: 0.67322 | R²: 0.11799 | sex, age, genetic principal components | — |
| PPM023398 | PGS005377 (DPRISM_T2DPRS_trainedforSAS_SASweights) |
PSS012157| South Asian Ancestry| 630 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.77 [1.47, 2.13] β: 0.56903 |
AUROC: 0.67322 | R²: 0.11799 | sex, age, genetic principal components | — |
| PPM023399 | PGS005373 (DPRISM_T2DPRS_trainedforSAS_AFRweights) |
PSS012161| South Asian Ancestry| 1,858 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.57 [2.23, 2.95] β: 0.94269 |
AUROC: 0.79407 | R²: 0.28515 | sex, age, genetic principal components | — |
| PPM023400 | PGS005374 (DPRISM_T2DPRS_trainedforSAS_AMRweights) |
PSS012161| South Asian Ancestry| 1,858 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.57 [2.23, 2.95] β: 0.94269 |
AUROC: 0.79407 | R²: 0.28515 | sex, age, genetic principal components | — |
| PPM023401 | PGS005375 (DPRISM_T2DPRS_trainedforSAS_EASweights) |
PSS012161| South Asian Ancestry| 1,858 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.57 [2.23, 2.95] β: 0.94269 |
AUROC: 0.79407 | R²: 0.28515 | sex, age, genetic principal components | — |
| PPM023402 | PGS005376 (DPRISM_T2DPRS_trainedforSAS_EURweights) |
PSS012161| South Asian Ancestry| 1,858 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.57 [2.23, 2.95] β: 0.94269 |
AUROC: 0.79407 | R²: 0.28515 | sex, age, genetic principal components | — |
| PPM023403 | PGS005377 (DPRISM_T2DPRS_trainedforSAS_SASweights) |
PSS012161| South Asian Ancestry| 1,858 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.57 [2.23, 2.95] β: 0.94269 |
AUROC: 0.79407 | R²: 0.28515 | sex, age, genetic principal components | — |
| PPM023214 | PGS005353 (DPRISM_T2DPRS_trainedforAFR_AFRweights) |
PSS012168| African Ancestry| 2,906 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 2.62 [2.3, 2.97] β: 0.96137 |
AUROC: 0.74575 | R²: 0.23196 | sex, age, genetic principal components | — |
| PPM023237 | PGS005356 (DPRISM_T2DPRS_trainedforAFR_EURweights) |
PSS012148| African Ancestry| 12,352 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Diabetic retinopathy | OR: 1.28 [1.18, 1.39] β: 0.24486 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023255 | PGS005359 (DPRISM_T2DPRS_trainedforAMR_AMRweights) |
PSS012156| Hispanic or Latin American Ancestry| 4,126 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 3.48 [3.02, 4.01] β: 1.24666 |
AUROC: 0.72336 | R²: 0.17962 | sex, age, genetic principal components | — |
| PPM023269 | PGS005358 (DPRISM_T2DPRS_trainedforAMR_AFRweights) |
PSS012151| Hispanic or Latin American Ancestry| 8,608 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 2.08 [1.73, 2.51] β: 0.73382 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
| PPM023312 | PGS005366 (DPRISM_T2DPRS_trainedforEAS_EURweights) |
PSS012154| East Asian Ancestry| 804 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 1.96 [1.6, 2.39] β: 0.67233 |
AUROC: 0.74954 | R²: 0.20701 | sex, age, genetic principal components | — |
| PPM023331 | PGS005365 (DPRISM_T2DPRS_trainedforEAS_EASweights) |
PSS012167| East Asian Ancestry| 3,634 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Type 2 diabetes | OR: 4.35 [3.89, 4.86] β: 1.46928 |
AUROC: 0.83429 | R²: 0.41128 | sex, age, genetic principal components | — |
| PPM023354 | PGS005368 (DPRISM_T2DPRS_trainedforEUR_AFRweights) |
PSS012150| European Ancestry| 41,736 individuals |
PGP000773 | Huerta-Chagoya A et al. medRxiv (2025) |Pre |
Reported Trait: Proliferative diabetic retinopathy | OR: 1.67 [1.44, 1.93] β: 0.51204 |
— | — | sex, age, genetic principal components | Restricted to T2D cases only. |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS012146 | — | — | [
|
— | South Asian (Punjabi Sikh) |
— | AIDHS, SDS | — |
| PSS012147 | — | — | [
|
— | South Asian | — | AllofUs | — |
| PSS012148 | — | — | [
|
— | African American or Afro-Caribbean (African American) |
— | AllofUs | — |
| PSS012149 | — | — | [
|
— | East Asian | — | AllofUs | — |
| PSS012150 | — | — | [
|
— | European (European American) |
— | AllofUs | — |
| PSS012151 | — | — | [
|
— | Hispanic or Latin American (Hispanic American) |
— | AllofUs | — |
| PSS012152 | — | — | [
|
— | East Asian (Japanese) |
— | BBJ | — |
| PSS012153 | — | — | [
|
— | African American or Afro-Caribbean (African American) |
— | BioMe | — |
| PSS012154 | — | — | [
|
— | East Asian | — | BioMe | — |
| PSS012155 | — | — | [
|
— | European (European American) |
— | BioMe | — |
| PSS012156 | — | — | [
|
— | Hispanic or Latin American (Hispanic American) |
— | BioMe | — |
| PSS012157 | — | — | [
|
— | South Asian | — | BioMe | — |
| PSS012158 | — | — | [
|
— | European (European American) |
— | BioVU | — |
| PSS012159 | — | — | [
|
— | East Asian (Chinese) |
— | CKB | — |
| PSS012160 | — | — | [
|
— | East Asian (Korean) |
— | KBA | — |
| PSS012161 | — | — | [
|
— | South Asian (British Indian) |
— | LOLIPOP | — |
| PSS012162 | — | — | [
|
— | African American or Afro-Caribbean | — | MGBB | — |
| PSS012163 | — | — | [
|
— | European (European American) |
— | MGBB | — |
| PSS012164 | — | — | [
|
— | Hispanic or Latin American | — | MGBB | — |
| PSS012165 | — | — | [
|
— | Hispanic or Latin American (Mexican) |
— | MXBB | — |
| PSS012166 | — | — | [
|
— | East Asian (Chinese, Malay) |
— | SDCS, SP2 | — |
| PSS012167 | — | — | [
|
— | East Asian (Korean) |
— | SNUH | — |
| PSS012168 | — | — | [
|
— | African unspecified (African) |
— | UKB | — |