PGS Publication: PGP000857

Publication Information (EuropePMC)
Title Characterizing genetic profiles for high triglyceride levels in U.S. patients of African ancestry.
PubMed ID 38795861(Europe PMC)
doi 10.1016/j.jlr.2024.100569
Publication Date May 23, 2024
Journal J Lipid Res
Author(s) Jiang L, Gangireddy S, Dickson AL, Xin Y, Yan C, Kawai V, Cox NJ, Linton MF, Wei WQ, Stein CM, Feng Q.
Released in PGS Catalog: Oct. 23, 2026

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported

External PGS Evaluated By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002287
(GRS_286_TG)
 PGP000313 |
Kamiza AB et al. Nat Med (2022)
 Triglyceride triglyceride measurement 286
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002287/ScoringFiles/PGS002287.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM038277 PGS002287
(GRS_286_TG)
 PSS013901|
African Ancestry|
15,373 individuals
 PGP000857 |
Jiang L et al. J Lipid Res (2024)
|Ext.		 Reported Trait: Triglyceride levels — — r: 0.12 — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013901 — — 15,373 individuals,
33.0 % Male samples
 Median = 59.0 years
Range = [48.0, 67.0] years		 African American or Afro-Caribbean — AllofUs —