| Experimental Factor Ontology (EFO) Information | |
| Identifier | EFO_0004462 |
| Description | A PR interval is an electrocardiography measurement which measures from the beginning of the P wave to the beginning of the QRS complex in the heart's electrical cycle | Trait category |
Cardiovascular measurement
|
| Synonym | PQ interval |
| Mapped terms |
2 mapped terms
|
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS000735 (PRS_PR) |
PGP000144 | Tadros R et al. Eur Heart J (2019) |
PR interval | PR interval | 44 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000735/ScoringFiles/PGS000735.txt.gz |
| PGS000904 (PRS582_PR) |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
PR interval | PR interval | 582 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000904/ScoringFiles/PGS000904.txt.gz |
| PGS000905 (PRS743_PR) |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
PR interval | PR interval | 743 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000905/ScoringFiles/PGS000905.txt.gz |
| PGS001521 (GBE_INI22330) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
PQ interval | PR interval | 391 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001521/ScoringFiles/PGS001521.txt.gz |
| PGS001904 (portability-PLR_ECG_PQ_interval) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
PQ interval | PR interval | 826 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001904/ScoringFiles/PGS001904.txt.gz |
| PGS002118 (portability-ldpred2_ECG_PQ_interval) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
PQ interval | PR interval | 413,539 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002118/ScoringFiles/PGS002118.txt.gz |
| PGS003499 (cont-decay-ECG_PQ_interval) |
PGP000457 | Ding Y et al. Nature (2023) |
PQ interval | PR interval | 979,739 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003499/ScoringFiles/PGS003499.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM001759 | PGS000735 (PRS_PR) |
PSS000905| European Ancestry| 1,185 individuals |
PGP000144 | Tadros R et al. Eur Heart J (2019) |
Reported Trait: Ajmaline-induced Type I Brugada syndrome electrocardiogram | OR: 1.017 [1.013, 1.022] | — | — | — | — |
| PPM001754 | PGS000735 (PRS_PR) |
PSS000904| European Ancestry| 1,257 individuals |
PGP000144 | Tadros R et al. Eur Heart J (2019) |
Reported Trait: PR slope | β: 0.22 (0.08) | — | — | — | — |
| PPM001750 | PGS000735 (PRS_PR) |
PSS000906| European Ancestry| 1,193 individuals |
PGP000144 | Tadros R et al. Eur Heart J (2019) |
Reported Trait: Baseline PR in non SCN5A mutation carriers | — | — | Correlation coefficent (r): 0.23 | — | — |
| PPM001752 | PGS000735 (PRS_PR) |
PSS000906| European Ancestry| 1,193 individuals |
PGP000144 | Tadros R et al. Eur Heart J (2019) |
Reported Trait: PR slope in non SCN5A mutation carriers | β: 0.16 (0.08) | — | Correlation coefficient (r): 0.09 | — | — |
| PPM002666 | PGS000904 (PRS582_PR) |
PSS001175| European Ancestry| 309,269 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Atrial fibrillation | OR: 0.95 β: -0.047 (0.009) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | Only 581 SNPs from the 582 SNP PRS were utilised. 1 SNP was not included due to low imputation quality. |
| PPM002667 | PGS000904 (PRS582_PR) |
PSS001178| European Ancestry| 290,252 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Distal conduction disease | OR: 1.11 β: 0.103 (0.019) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | Only 581 SNPs from the 582 SNP PRS were utilised. 1 SNP was not included due to low imputation quality. |
| PPM002668 | PGS000904 (PRS582_PR) |
PSS001176| European Ancestry| 309,041 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Atrioventricular preexcitation | OR: 0.85 β: -0.168 (0.057) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | Only 581 SNPs from the 582 SNP PRS were utilised. 1 SNP was not included due to low imputation quality. |
| PPM002669 | PGS000904 (PRS582_PR) |
PSS001179| European Ancestry| 309,241 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Implantable cardioverter defibrillator | OR: 1.09 β: 0.086 (0.04) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | Only 581 SNPs from the 582 SNP PRS were utilised. 1 SNP was not included due to low imputation quality. |
| PPM002670 | PGS000904 (PRS582_PR) |
PSS001180| European Ancestry| 309,246 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Mitral valve prolapse | OR: 1.1 β: 0.093 (0.044) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | Only 581 SNPs from the 582 SNP PRS were utilised. 1 SNP was not included due to low imputation quality. |
| PPM002671 | PGS000904 (PRS582_PR) |
PSS001181| European Ancestry| 305,471 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Non-ischemic cardiomyopathy | OR: 0.95 β: -0.051 (0.024) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | Only 581 SNPs from the 582 SNP PRS were utilised. 1 SNP was not included due to low imputation quality. |
| PPM002672 | PGS000904 (PRS582_PR) |
PSS001182| European Ancestry| 309,270 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Pacemaker | OR: 1.06 β: 0.062 (0.016) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | Only 581 SNPs from the 582 SNP PRS were utilised. 1 SNP was not included due to low imputation quality. |
| PPM002673 | PGS000904 (PRS582_PR) |
PSS001183| European Ancestry| 309,255 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Valve disease | OR: 1.03 β: 0.03 (0.013) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | Only 581 SNPs from the 582 SNP PRS were utilised. 1 SNP was not included due to low imputation quality. |
| PPM002674 | PGS000905 (PRS743_PR) |
PSS001175| European Ancestry| 309,269 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Atrial fibrillation | OR: 0.94 β: -0.058 (0.009) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | — |
| PPM002675 | PGS000905 (PRS743_PR) |
PSS001178| European Ancestry| 290,252 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Distal conduction disease | OR: 1.11 β: 0.105 (0.019) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | — |
| PPM002676 | PGS000905 (PRS743_PR) |
PSS001176| European Ancestry| 309,041 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Atrioventricular preexcitation | OR: 0.83 β: -0.191 (0.057) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | — |
| PPM002677 | PGS000905 (PRS743_PR) |
PSS001177| European Ancestry| 309,246 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Coronary artery disease | OR: 0.99 β: -0.014 (0.007) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | — |
| PPM002678 | PGS000905 (PRS743_PR) |
PSS001182| European Ancestry| 309,270 individuals |
PGP000236 | Ntalla I et al. Nat Commun (2020) |
Reported Trait: Pacemaker | OR: 1.06 β: 0.056 (0.016) |
— | — | Baseline age, sex, genotyping array, trait-related principal components | — |
| PPM005300 | PGS001521 (GBE_INI22330) |
PSS004966| African Ancestry| 120 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: PQ interval | — | — | R²: 0.14397 [0.12818, 0.15975] Incremental R2 (full-covars): 0.00024 PGS R2 (no covariates): 0.01367 [0.00807, 0.01928] |
age, sex, UKB array type, Genotype PCs | — |
| PPM005301 | PGS001521 (GBE_INI22330) |
PSS004967| East Asian Ancestry| 68 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: PQ interval | — | — | R²: 0.2664 [0.23052, 0.30228] Incremental R2 (full-covars): -0.00945 PGS R2 (no covariates): 0.00783 [-0.00049, 0.01615] |
age, sex, UKB array type, Genotype PCs | — |
| PPM005302 | PGS001521 (GBE_INI22330) |
PSS004968| European Ancestry| 834 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: PQ interval | — | — | R²: 0.10209 [0.09497, 0.10922] Incremental R2 (full-covars): 0.04534 PGS R2 (no covariates): 0.05149 [0.04615, 0.05684] |
age, sex, UKB array type, Genotype PCs | — |
| PPM005303 | PGS001521 (GBE_INI22330) |
PSS004969| South Asian Ancestry| 193 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: PQ interval | — | — | R²: 0.13589 [0.12179, 0.15] Incremental R2 (full-covars): -0.01928 PGS R2 (no covariates): 0.00031 [-0.00047, 0.00108] |
age, sex, UKB array type, Genotype PCs | — |
| PPM005304 | PGS001521 (GBE_INI22330) |
PSS004970| European Ancestry| 3,353 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: PQ interval | — | — | R²: 0.07982 [0.0759, 0.08375] Incremental R2 (full-covars): 0.02363 PGS R2 (no covariates): 0.02488 [0.02256, 0.0272] |
age, sex, UKB array type, Genotype PCs | — |
| PPM010115 | PGS001904 (portability-PLR_ECG_PQ_interval) |
PSS009364| European Ancestry| 992 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.173 [0.1113, 0.2333] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010116 | PGS001904 (portability-PLR_ECG_PQ_interval) |
PSS009138| European Ancestry| 181 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.1945 [0.041, 0.3389] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010117 | PGS001904 (portability-PLR_ECG_PQ_interval) |
PSS008692| European Ancestry| 217 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.2467 [0.1108, 0.3736] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010118 | PGS001904 (portability-PLR_ECG_PQ_interval) |
PSS008466| Greater Middle Eastern Ancestry| 25 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.2876 [-0.7969, 0.9331] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010119 | PGS001904 (portability-PLR_ECG_PQ_interval) |
PSS008246| South Asian Ancestry| 159 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.09 [-0.0776, 0.2527] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010120 | PGS001904 (portability-PLR_ECG_PQ_interval) |
PSS008024| East Asian Ancestry| 73 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.0694 [-0.2047, 0.3335] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010121 | PGS001904 (portability-PLR_ECG_PQ_interval) |
PSS007810| African Ancestry| 49 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.212 [-0.1676, 0.5368] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM010122 | PGS001904 (portability-PLR_ECG_PQ_interval) |
PSS008914| African Ancestry| 61 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.2774 [-0.0331, 0.539] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011801 | PGS002118 (portability-ldpred2_ECG_PQ_interval) |
PSS008692| European Ancestry| 217 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.2529 [0.1173, 0.3793] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011799 | PGS002118 (portability-ldpred2_ECG_PQ_interval) |
PSS009364| European Ancestry| 992 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.1997 [0.1385, 0.2593] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011800 | PGS002118 (portability-ldpred2_ECG_PQ_interval) |
PSS009138| European Ancestry| 181 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.2082 [0.0553, 0.3516] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011802 | PGS002118 (portability-ldpred2_ECG_PQ_interval) |
PSS008466| Greater Middle Eastern Ancestry| 25 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.1708 [-0.8377, 0.9152] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011803 | PGS002118 (portability-ldpred2_ECG_PQ_interval) |
PSS008246| South Asian Ancestry| 159 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.116 [-0.0515, 0.2771] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011804 | PGS002118 (portability-ldpred2_ECG_PQ_interval) |
PSS008024| East Asian Ancestry| 73 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.1237 [-0.1517, 0.3812] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011805 | PGS002118 (portability-ldpred2_ECG_PQ_interval) |
PSS007810| African Ancestry| 49 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.1518 [-0.2274, 0.491] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011806 | PGS002118 (portability-ldpred2_ECG_PQ_interval) |
PSS008914| African Ancestry| 61 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: PQ interval | — | — | Partial Correlation (partial-r): 0.1868 [-0.1282, 0.4676] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM017427 | PGS003499 (cont-decay-ECG_PQ_interval) |
PSS010860| European Ancestry| 995 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: PQ interval | — | — | partial-R2: 0.07 | sex, age, deprivation index, PC1-16 | — |
| PPM017511 | PGS003499 (cont-decay-ECG_PQ_interval) |
PSS010776| European Ancestry| 180 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: PQ interval | — | — | partial-R2: 0.05 | sex, age, deprivation index, PC1-16 | — |
| PPM017595 | PGS003499 (cont-decay-ECG_PQ_interval) |
PSS010608| European Ancestry| 213 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: PQ interval | — | — | partial-R2: 0.04 | sex, age, deprivation index, PC1-16 | — |
| PPM017679 | PGS003499 (cont-decay-ECG_PQ_interval) |
PSS010524| Greater Middle Eastern Ancestry| 25 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: PQ interval | — | — | partial-R2: 0.32 | sex, age, deprivation index, PC1-16 | — |
| PPM017763 | PGS003499 (cont-decay-ECG_PQ_interval) |
PSS010188| European Ancestry| 103 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: PQ interval | — | — | partial-R2: 0.07 | sex, age, deprivation index, PC1-16 | — |
| PPM017847 | PGS003499 (cont-decay-ECG_PQ_interval) |
PSS010440| South Asian Ancestry| 159 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: PQ interval | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
| PPM017931 | PGS003499 (cont-decay-ECG_PQ_interval) |
PSS010356| East Asian Ancestry| 73 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: PQ interval | — | — | partial-R2: 0.02 | sex, age, deprivation index, PC1-16 | — |
| PPM018015 | PGS003499 (cont-decay-ECG_PQ_interval) |
PSS010272| African Ancestry| 49 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: PQ interval | — | — | partial-R2: 0.05 | sex, age, deprivation index, PC1-16 | — |
| PPM018099 | PGS003499 (cont-decay-ECG_PQ_interval) |
PSS010692| African Ancestry| 61 individuals |
PGP000457 | Ding Y et al. Nature (2023) |
Reported Trait: PQ interval | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS010272 | — | — | 49 individuals, 31.0 % Male samples |
Mean = 48.8 years Sd = 6.4 years |
African American or Afro-Caribbean | Caribbean | UKB | — |
| PSS008914 | — | — | 61 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS000904 | Intravenous ajmaline was administered at consecutive boluses of 10 mg/min. A 10-s ECG was recorded ∼1 min after each bolus using a GE Healthcare electrocardiograph. The test was stopped when the target dose of 1 mg/kg rounded up to the next 10 mg was reached, if ventricular arrhythmia occurred, or at the manifestation of a Type I BrS pattern, defined as an ST elevation >2 mm with a coved morphology in any lead among V1–V2 in the 2nd to 4th intercostal spaces.12 | — | 1,257 individuals | — | European | — | Amsterdam | — |
| PSS000905 | Intravenous ajmaline was administered at consecutive boluses of 10 mg/min. A 10-s ECG was recorded ∼1 min after each bolus using a GE Healthcare electrocardiograph. The test was stopped when the target dose of 1 mg/kg rounded up to the next 10 mg was reached, if ventricular arrhythmia occurred, or at the manifestation of a Type I BrS pattern, defined as an ST elevation >2 mm with a coved morphology in any lead among V1–V2 in the 2nd to 4th intercostal spaces.15 | — | 1,185 individuals | — | European | — | Amsterdam | — |
| PSS000906 | Intravenous ajmaline was administered at consecutive boluses of 10 mg/min. A 10-s ECG was recorded ∼1 min after each bolus using a GE Healthcare electrocardiograph. The test was stopped when the target dose of 1 mg/kg rounded up to the next 10 mg was reached, if ventricular arrhythmia occurred, or at the manifestation of a Type I BrS pattern, defined as an ST elevation >2 mm with a coved morphology in any lead among V1–V2 in the 2nd to 4th intercostal spaces.13 | — | 1,193 individuals | — | European | — | Amsterdam | — |
| PSS008024 | — | — | 73 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS010692 | — | — | 61 individuals, 64.0 % Male samples |
Mean = 49.5 years Sd = 6.5 years |
African unspecified | Nigerian | UKB | — |
| PSS004966 | — | — | 120 individuals | — | African unspecified | — | UKB | — |
| PSS004967 | — | — | 68 individuals | — | East Asian | — | UKB | — |
| PSS004968 | — | — | 834 individuals | — | European | non-white British ancestry | UKB | — |
| PSS004969 | — | — | 193 individuals | — | South Asian | — | UKB | — |
| PSS004970 | — | — | 3,353 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS010188 | — | — | 103 individuals, 55.0 % Male samples |
Mean = 56.0 years Sd = 6.1 years |
European | Ashkenazi | UKB | — |
| PSS008692 | — | — | 217 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS010440 | — | — | 159 individuals, 65.0 % Male samples |
Mean = 51.1 years Sd = 8.2 years |
South Asian | Indian | UKB | — |
| PSS007810 | — | — | 49 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS008466 | — | — | 25 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS010860 | — | — | 995 individuals, 51.0 % Male samples |
Mean = 55.4 years Sd = 7.5 years |
European | white British | UKB | — |
| PSS009364 | — | — | 992 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS010608 | — | — | 213 individuals, 48.0 % Male samples |
Mean = 53.8 years Sd = 7.4 years |
European | Italian | UKB | — |
| PSS010356 | — | — | 73 individuals, 34.0 % Male samples |
Mean = 50.3 years Sd = 7.1 years |
East Asian | Chinese | UKB | — |
| PSS001175 | Cases were individuals with atrial fibrillation. Disease status was ascertained based on data from baseline interviews, hospital diagnosis codes (ICD-9 and ICD-10), cause of death codes (ICD-10), and operation codes. Details of individual selections and disease definitions are described in Supplementary Data 23. | — | [
|
— | European | — | UKB | — |
| PSS001176 | Cases were individuals with atrioventricular preexcitation. Disease status was ascertained based on data from baseline interviews, hospital diagnosis codes (ICD-9 and ICD-10), cause of death codes (ICD-10), and operation codes. Details of individual selections and disease definitions are described in Supplementary Data 23. | — | [
|
— | European | — | UKB | — |
| PSS001177 | Cases were individuals with congential artery disease. Disease status was ascertained based on data from baseline interviews, hospital diagnosis codes (ICD-9 and ICD-10), cause of death codes (ICD-10), and operation codes. Details of individual selections and disease definitions are described in Supplementary Data 23. | — | [
|
— | European | — | UKB | — |
| PSS001178 | Cases were individuals with distal conduction disease. Disease status was ascertained based on data from baseline interviews, hospital diagnosis codes (ICD-9 and ICD-10), cause of death codes (ICD-10), and operation codes. Details of individual selections and disease definitions are described in Supplementary Data 23. | — | [
|
— | European | — | UKB | — |
| PSS001179 | Cases were individuals with implantable cardioverter defibrillators. Disease status was ascertained based on data from baseline interviews, hospital diagnosis codes (ICD-9 and ICD-10), cause of death codes (ICD-10), and operation codes. Details of individual selections and disease definitions are described in Supplementary Data 23. | — | [
|
— | European | — | UKB | — |
| PSS001180 | Cases were individuals with mitral valve prolapse. Disease status was ascertained based on data from baseline interviews, hospital diagnosis codes (ICD-9 and ICD-10), cause of death codes (ICD-10), and operation codes. Details of individual selections and disease definitions are described in Supplementary Data 23. | — | [
|
— | European | — | UKB | — |
| PSS001181 | Cases were individuals with non-ischemic cardiomyopathy. Disease status was ascertained based on data from baseline interviews, hospital diagnosis codes (ICD-9 and ICD-10), cause of death codes (ICD-10), and operation codes. Details of individual selections and disease definitions are described in Supplementary Data 23. | — | [
|
— | European | — | UKB | — |
| PSS001182 | Cases were individuals with a pacemaker. Disease status was ascertained based on data from baseline interviews, hospital diagnosis codes (ICD-9 and ICD-10), cause of death codes (ICD-10), and operation codes. Details of individual selections and disease definitions are described in Supplementary Data 23. | — | [
|
— | European | — | UKB | — |
| PSS001183 | Cases were individuals with valve disease. Disease status was ascertained based on data from baseline interviews, hospital diagnosis codes (ICD-9 and ICD-10), cause of death codes (ICD-10), and operation codes. Details of individual selections and disease definitions are described in Supplementary Data 23. | — | [
|
— | European | — | UKB | — |
| PSS009138 | — | — | 181 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS008246 | — | — | 159 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS010776 | — | — | 180 individuals, 41.0 % Male samples |
Mean = 53.2 years Sd = 6.5 years |
European | Polish | UKB | — |
| PSS010524 | — | — | 25 individuals, 64.0 % Male samples |
Mean = 52.6 years Sd = 6.8 years |
Greater Middle Eastern (Middle Eastern, North African or Persian) | Iranian | UKB | — |