Trait: mononeuropathy

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009558
Description Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ischemia; traumatic injury; compression; connective tissue diseases; cumulative trauma disorders; and other conditions. [MESH: D020422]
Trait category
Neurological disorder
Synonym mononeuropathy
Mapped terms 13 mapped terms
  • DOID:1188
  • ICD10:G56
  • ICD10:G57
  • ICD10:G58
  • ICD10:G58.9
  • MEDGEN:99214
  • MESH:D020422
  • MONDO:0001397
  • MeSH:D020422
  • MedDRA:10062203
  • SCTID:128189008
  • UMLS:C0494491
  • icd11.foundation:1866592137

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Ancestry legend
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Multi-ancestry (excluding European)
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Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004453
(disease.G56.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 G56 (Mononeuropathies of upper limb) mononeuropathy 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004453/ScoringFiles/PGS004453.txt.gz
PGS004523
(meta.G56.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 G56 (Mononeuropathies of upper limb) mononeuropathy 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004523/ScoringFiles/PGS004523.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM020568 PGS004453
(disease.G56.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: G56 (Mononeuropathies of upper limb) OR: 1.2757 — — — —
PPM020638 PGS004523
(meta.G56.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: G56 (Mononeuropathies of upper limb) OR: 1.41928 — — — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS011364 — — 56,192 individuals — European — UKB —